Publications

SNAC values the open sharing of scientific knowledge. We regularly publish the findings of our research in respected journals and contribute to international academic meetings such as MICCAI, ISMRM, and ECTRIMS. We have deep collaborations with academics at the University of Sydney’s Brain and Mind Centre and with other imaging centres across the globe.

Journal Papers

Multiple sclerosis: structural and functional integrity of the visual system following alemtuzumab therapy

Chenyu Wang, Joshua Barton, Kain Kyle, Linda Ly, Yael Barnett, Hans-Peter Hartung, Stephen W Reddel, Heidi Beadnall, Marinda Taha, Alexander Klistorner, Michael Harry Barnett

Journal of Neurology, Neurosurgery & Psychiatry (2021)

FOD-Net: A Deep Learning Method for Fiber Orientation Distribution Angular Super Resolution

Rui Zeng, Jinglei Lv , He Wang, Luping Zhou, Michael Barnett, Fernando Calamante, Chenyu Wang

bioRxiv (2021)

Interferon-β is less effective than other drugs in controlling the rate of retinal ganglion cell loss in MS

Yuyi You, Michael H. Barnett, Con Yiannikas, John DE Parratt, Jim G. Matthews, Stuart L. Graham, Alexander Klistorner.

Neurology-Neuroimmunology Neuroinflammation 8, no. 3 (2021)

Multiple Sclerosis Lesion Analysis in Brain Magnetic Resonance Images: Techniques and Clinical Applications

Yang Ma, Chaoyi Zhang, Mariano Cabezas, Yang Song, Zihao Tang, Dongnan Liu, Weidong Cai, Michael Barnett, Chenyu Wang

arXiv preprint arXiv:2104.10029 (2021)

Differentiating axonal loss and demyelination in chronic MS lesions: A novel approach using single streamline diffusivity analysis

Samuel Klistorner, Michael H. Barnett, Jakob Wasserthal, Con Yiannikas, Joshua Barton, John Parratt, Yuyi You, Stuart L. Graham, Alexander Klistorner

PLoS ONE16, no. 1 (2021): e0244766

Latency of Multifocal Visual Evoked Potential in Multiple Sclerosis: A Visual Pathway Biomarker for Clinical Trials of Remyelinating Therapies

Klistorner Alexander, James D. Triplett, Michael H. Barnett, Con Yiannikas, Joshua Barton, John Parratt, Yuyi You, & Stuart L. Graham.

Journal of Clinical Neurophysiology 38, no. 3 (2021): 186-191

Expansion of chronic lesions is linked to disease progression in relapsing–remitting multiple sclerosis patients

Samuel Klistorner, Michael H. Barnett, Con Yiannikas, Joshua Barton, John Parratt, Yuyi You, Stuart L. Graham, Alexander Klistorner.

Multiple Sclerosis Journal (2020): 1352458520974357

MRI biomarkers of disease progression in multiple sclerosis: old dog, new tricks?

Yael Barnett, Justin Y. Garber, & Michael H. Barnett

Quantitative imaging in medicine and surgery 10, no. 2 (2020): 527

Regional callosal integrity and bilaterality of limb weakness in amyotrophic lateral sclerosis

Sicong Tu, Chenyu Wang, Ricarda A.L. Menke, Kevin Talbot, Michael Barnett, Matthew C. Kiernan & Martin R. Turner

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21, no. 5-6 (2020): 396-402

Serum Exosome MicroRNAs Predict Multiple Sclerosis Disease Activity after Fingolimod Treatment

Saeideh Ebrahimkhani, Heidi N. Beadnall, Chenyu Wang, Catherine M. Suter, Michael H. Barnett, Michael E. Buckland & Fatemeh Vafaee

Molecular neurobiology 57, no. 2 (2020): 1245-1258

Salient Central Lesion Volume: A Standardized Novel Fully Automated Proxy for Brain FLAIR Lesion Volume in Multiple Sclerosis

Michael G. Dwyer, Niels Bergsland, Deepa P. Ramasamy, Bianca Weinstock‐Guttman, Michael H. Barnett, Chenyu Wang, Davorka Tomic, Diego Silva, Robert Zivadinov

Journal of Neuroimaging 29, no. 5 (2019): 615-623

Lesion activity and chronic demyelination are the major determinants of brain atrophy in MS

Chenyu Wang, Michael H. Barnett, Con Yiannikas, Joshua Barton, John Parratt, Yuyi You, Stuart L. Graham, Alexander Klistorner

Neurology-Neuroimmunology Neuroinflammation 6, no. 5 (2019): e593

Imaging the multiple sclerosis lesion: insights into pathogenesis, progression and repair

Chenyu Tim Wang, Michael Barnett, Yael Barnett

Current opinion in neurology 32, no. 3 (2019): 338-345

Demyelination precedes axonal loss in the transneuronal spread of human neurodegenerative disease

Yuyi You, Chitra Joseph, Chenyu Wang, Vivek Gupta, Sidong Liu, Con Yiannikas, Brian E Chua, Nitin Chitranshi, Ting Shen, Yogita Dheer, Alessandro Invernizzi, Robert Borotkanics, Michael Barnett, Stuart L Graham, Alexander Klistorner

Brain142, no. 2 (2019): 426-442

Comparing longitudinal brain atrophy measurement techniques in a real-world multiple sclerosis clinical practice cohort: towards clinical integration?

H N Beadnall, C Wang, W Van Hecke, A Ribbens, T Billiet, M H Barnett

Therapeutic advances in neurological disorders 12 (2019): 1756286418823462

Diffusivity in the core of chronic multiple sclerosis lesions

Alexander Klistorner, Chenyu Wang, Con Yiannikas, John Parratt, Joshua Barton, Yuyi You, Stuart L. Graham, Michael H. Barnett

PLoS ONE13, no. 4 (2018): 1–20

White matter tract-specific quantitative analysis in multiple sclerosis: Comparison of optic radiation reconstruction techniques

Chenyu Wang, Alexander Klistorner, Linda Ly, Michael H. Barnett

PLoS ONE13, no. 1 (2018): 1–19

Successful implementation of an automated electronic support system for patient safety monitoring: The alemtuzumab in multiple sclerosis safety systems (AMS3) study

Stephen W Reddel, Michael H Barnett, Sean Riminton, Tej Dugal, Katherine Buzzard, Chenu Tim Wang, Fiona Fitzgerald, Heidi N Beadnall, Diane Erickson, David Gahan, Daniel Wang, Toby Ackland, Richard Thompson

Multiple Sclerosis Journal(2018), 135245851878367

Evidence of progressive tissue loss in the core of chronic MS lesions: A longitudinal DTI study☆

Alexander Klistorner, Chenyu Wang, Con Yiannikas, John Parratt, Michael Dwyer, Joshua Barton, Stuart L. Graham, Yuyi You, Sidong Liu, Michael H. Barnett

NeuroImage: Clinical17, no. October 2017 (2018): 1028–35

The evolution of “No Evidence of Disease Activity” in multiple sclerosis

G. Lu, H. N. Beadnall, J. Barton, T. A. Hardy, C. Wang, M. H. Barnett

Multiple Sclerosis and Related Disorders20, no. October 2017 (2018): 231–38

Progression of retinal ganglion cell loss in multiple sclerosis is associated with new lesions in the optic radiations

A. Klistorner, E. C. Graham, C. Yiannikas, M. Barnett, J. Parratt, R. Garrick, C. Wang, Y. You, S. L. Graham

European journal of neurology24, no. 11 (2017): 1392-1398

MRI FLAIR lesion segmentation in multiple sclerosis: Does automated segmentation hold up with manual annotation?

Christine Egger, Roland Opfer, Chenyu Wang, Timo Kepp, Maria Pia Sormanie, Lothar Spies, Michael Barnett, Sven Schippling

NeuroImage: Clinical13 (2017): 264–70

Tumefactive demyelination following treatment for relapsing multiple sclerosis with alemtuzumab

Joshua Barton, Todd A. Hardy, Sean Riminton, Stephen W. Reddel, Yael Barnett, Alasdair Coles, Michael H. Barnett

Neurology 88, no. 10 (2017): 1004-1006

Effect of Fingolimod on Brain Volume Loss in Patients with Multiple Sclerosis

Nicola De Stefano, Diego G. Silva & Michael H. Barnett

CNS Drugs31, no. 4 (2017): 289–305

Vestibulo-ocular reflex deficits with medial longitudinal fasciculus lesions

Swee T. Aw, Luke Chen, Michael J. Todd, Michael H. Barnett & G. Michael Halmagyi

Journal of Neurology264, no. 10 (2017): 2119–29

Progressive Injury in Chronic Multiple Sclerosis Lesions Is Gender-Specific: A DTI Study

Alexander Klistorner, Chenyu Wang, Con Yiannikas, Stuart L. Graham, John Parratt, Michael H. Barnett

PLoS ONE11, no. 2 (2016): 1–11

Diffusivity in multiple sclerosis lesions: At the cutting edge?

Alexander Klistorner, Chenyu Wang, Vera Fofanova, Michael H. Barnett, Con Yiannikas, JohnParratt, Yuyi You, Stuart L.Graham

NeuroImage: Clinical12 (2016): 219–26

Automated brain volumetrics in multiple sclerosis: a step closer to clinical application

C Wang, H N Beadnall, S N Hatton, G Bader, D Tomic, D G Silva, H Barnett

Journal of Neurology, Neurosurgery and Psychiatry87, no. 7 (2016): 754–57

Two Time Point MS Lesion Segmentation in Brain MRI: An Expectation-Maximization Framework

Saurabh Jain, Annemie Ribbens, Diana M. Sima, Melissa Cambron, Jacques De Keyser Chenyu Wang, Michael H. Barnett, Sabine Van Huffel, Frederik Maes and Dirk Smeets

Frontiers in Neuroscience10, no. DEC (2016): 1–11

Radiological differentiation of optic neuritis with myelin oligodendrocyte glycoprotein antibodies, aquaporin-4 antibodies, and multiple sclerosis

Sudarshini Ramanathan, Kristina Prelog, Elizabeth H Barnes, Esther M Tantsis, Stephen W Reddel, Andrew PD Henderson, Steve Vucic, Mark P Gorman, Leslie A Benson, Gulay Alper, Catherine J Riney, Michael Barnett, John DE Parratt, Todd A Hardy, Richard J Leventer, Vera Merheb, Margherita Nosadini, Victor SC Fung, Fabienne Brilot, Russell C Dale

Multiple Sclerosis22, no. 4 (2016): 470–82

Wallerian Degeneration in the Corticospinal Tract Following Tumefactive Demyelination: Conventional and Advanced Magnetic Resonance Imaging

Todd A Hardy, Chenyu Wang, Heidi N Beadnall, Jim Lagopoulos, Yael Barnett, Alexander Klistorner, Michael H Barnett

Canadian Journal of Neurological Sciences43, no. 5 (2016): 726–27

Atypical inflammatory demyelinating syndromes of the CNS

Dr Todd A Hardy PhD, Stephen W Reddel PhD, Michael H Barnett PhD, Jacqueline Palace DM, Prof Claudia F Lucchinetti MD Prof Brian G Weinshenker MD

The Lancet Neurology15, no. 9 (2016): 967–81

Decoding Diffusivity in Multiple Sclerosis: Analysis of Optic Radiation Lesional and Non-Lesional White Matter

Alexander Klistorner, Nikitha Vootakuru, Chenyu Wang, Con Yiannikas, Stuart L. Graham, John Parratt, Raymond Garrick, Netta Levin, Lynette Masters, Jim Lagopoulos, Michael H. Barnett

PLoS ONE10, no. 3 (2015): 1–24

Axonal conduction in multiple sclerosis: A combined magnetic resonance imaging and electrophysiological study of the medial longitudinal fasciculus

Chenyu Wang, David Paling, Luke Chen, Sean N Hatton, Jim Lagopoulos, Swee T Aw, Matthew C Kiernan, Michael H Barnett

Multiple Sclerosis21, no. 7 (2015): 905–15

Emotional Processing, P50 Sensory Gating, and Social Functioning in Bipolar Disorder

Laura Vuillier, Daniel F. Hermens, Kate Chitty, Chenyu Wang, Manreena Kaur, Philip B. Ward, Rachael Degabriele, Ian B. Hickie, Jim Lagopoulos

Clinical EEG and Neuroscience46, no. 2 (2015): 81–87

Axonal loss of retinal neurons in multiple sclerosis associated with optic radiation lesions

Alexander Klistorner, Prima Sriram, Nikitha Vootakuru, Chenyu Wang, Michael H. Barnett, Raymond Garrick, John Parratt, Netta Levin, Noa Raz, Anneke Van der Walt, Lynette Masters, Stuart L. Graham, Con Yiannikas

Neurology82, no. 24 (2014): 2165–72

Conventional and Advanced Imaging in Neuromyelitis Optica

Y. Barnett, I.J. Sutton, M. Ghadiri, L. Masters, R. Zivadinov and M.H. Barnett

American Journal of Neuroradiology35, no. 8 (2014): 1458–66

Latency of Multifocal Visual Evoked Potentials in Nonoptic Neuritis Eyes of Multiple Sclerosis Patients Associated With Optic Radiation Lesions

Daniah Alshowaeir; Con Yiannikas; Raymond Garrick; John Parratt; Michael H. Barnett; Stuart L. Graham; Alexander Klistorner

Investigative Ophthalmology and Visual Science55, no. 6 (2014): 3758–64

A Topographical Relationship Between Visual Field Defects and Optic Radiation Changes in Glaucoma

Megha Kaushik; Stuart L. Graham; Chenyu Wang; Alexander Klistorner

Investigative Ophthalmology and Visual Science55, no. 9 (2014): 5770–75

Relationship between Optical Coherence Tomography and Electrophysiology of the Visual Pathway in Non-Optic Neuritis Eyes of Multiple Sclerosis Patients

Prema Sriram, Chenyu Wang, Con Yiannikas, Raymond Garrick, Michael Barnett, John Parratt, Stuart L. Graham, Hemamalini Arvind, Alexander Klistorner

PLoS ONE9, no. 8 (2014): 1–11

Inner Nuclear Layer Thickening Is Inversley Proportional to Retinal Ganglion Cell Loss in Optic Neuritis

Megha Kaushik, Chen Yu Wang, Michael H. Barnett, Raymond Garrick, John Parratt, Stuart L. Graham, Prema Sriram, Con Yiannikas, Alexandr Klistorner

PLoS ONE8, no. 10 (2013): 1–9

The thalamus and multiple sclerosis: modern views on pathologic, imaging, and clinical aspects

Alireza Minagar, Michael H. Barnett, Ralph H.B. Benedict, Daniel Pelletier, Istvan Pirko, Mohamad Ali Sahraian, Elliott Frohman, Robert Zivadinov

Neurology80, no. 2 (2013): 210–19

Transsynaptic Retinal Degeneration in Optic Neuropathies: Optical Coherence Tomography Study

Stuart L. Graham; Chenyu Wang; Con Yiannikas; Raymond Garrick; Alexander Klistorner

Investigative Ophthalmology and Visual Science53, no. 3 (2012): 1271–75

Conference Papers/Abstracts

Multiple Sclerosis Lesion Filling Using a Non-lesion Attention Based Convolutional Network

Hao Xiong, Chaoyue Wang, Michael Barnett, Chenyu Wang

International Conference on Neural Information Processing. Cham: Springer, (2020): 448-460.

Assessment of brain atrophy and lesion burden with clinical outcomes in multiple sclerosis real-world practice: The NeuroSTREAM MSBase retrospective, longitudinal study

Michael Barnett, Niels Bergsland, Bianca Weinstock-Guttman, Helmut Butzkueven, Tomas Kalincik, Patricia Desmond, Frank Gaillard, Vincent Van Pesch, Serkan Ozakbas, Juan Ignacio Rojas, Cavit Boz, Ayse Altintas, Chenyu Wang, Michael Dwyer, Suzie Yang, Dejan Jakimovski, Kain Kyle, Deepa Ramasamy, Robert Zivadinov

Neurology (2021)

Masked Multi-Task Network for Case-Level Intracranial Hemorrhage Classification in Brain CT Volumes

Dongang Wang, Chenyu Wang, Lynette Masters, Michael Barnett

Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. Cham: Springer, (2020):145–154

Implications of registration of white matter structures for ms connectome analysis

Garber J, Barnett M, Calamante F, Wang C.

In Multiple Sclerosis Journal, Vol. 26, pp. 399-400. 1 Olivers Yerd,55 City Road, London EC1Y 1SP, England:Sage Publications Ltd

Longitudinal electronic patient-reported outcome collection in a treated relapsing multiple sclerosis cohort: Comparison with clinical, cognitive and quantitative magnetic resonance imaging metrics

Beadnall, H. N., Wang, C., Hardy, T. A., Reddel, S., Barnett, M. H.

In Multiple Sclerosis Journal, Vol. 26, pp. NP50-NP50. 1 Olivers Yerd,55 City Road, London EC1Y 1SP, England:Sage Publications Ltd

Cortical volume, cortical thickness and cognitive performance: Comparison of an early real-world relapsing multiple sclerosis cohort and matched healthy controls

Beadnall, H. N., Wang, C., Hardy, T. A., Reddel, S., Barnett, M. H.

In Multiple Sclerosis Journal, Vol. 26, pp. NP57-NP57. 1 Olivers Yerd,55 City Road, London EC1Y 1SP, England:Sage Publications Ltd

VISIONARY-MS: A Phase 2 Clinical Trial Of Catalytic Gold Nanocrystals, CNM-Au8, For The Treatment Of Chronic Optic Neuropathy

Beadnall, H., Hotchkin, M., Klistorner, A., Barnett, M., Sergott, R., Rynders, A., Rynders, A., Adamson, J., Ho, KS., Mortenson, MG., Glanzman, R.

In Multiple Sclerosis Journal, Vol. 26, pp. 52-53. 1 Olivers Yerd,55 City Road, London EC1Y 1SP, England:Sage Publications Ltd

Accurate Brain Extraction Using 3D U-Net with Encoded Spatial Information

Hualei Shen, Chenyu Wang, Kain Kyle, Chun-Chien Shieh, Lynette Masters, Fernando Calamante, Dacheng Tao, and Michael Barnett

ISMRM 28th Annual Meeting, Paris, France,08-13 August 2020

Attention-based Semantic Segmentation of Thigh Muscle with T1-weighted Magnetic Resonance Imaging

Zihao Tang, Kain Kyle , Michael H Barnett , Ché Fornusek , Weidong Cai, Chenyu Wang

ISMRM 28th Annual Meeting, Paris, France,08-13 August 2020

Improving the accuracy of brain tissue loss assessment in patients with multiple sclerosis: a role for diffusion imaging

Wang, C., A. Klistorner, H. N. Beadnall, J. Barton, L. Ly, S. Reddel, and M. H. Barnett

In Multiple Sclerosis Journal, Vol. 23, pp. 267-268. 1 Olivers Yerd,55 City Road, London EC1Y 1SP, England:Sage Publications Ltd

Fully automated lesion segmentation using heavily trained 3D convolutional neural networks are equivalent to manual expert segmentations

Krüger, J., Opfer, R., Gessert, N. T., Ostwaldt, A. C., Walker-Egger, C., Manogaran, P., Wang, C., Barnett, M., Schlaefer, A & Schippling, S. (2019)

ECTRIMS 2019, Stockholm,11-13 September 2019

Magnetic resonance spectroscopy correlates with DTI and brain atrophy in multiple sclerosis

Kyle, K., Wang, C., Beadnall, H., Ghadiri, M., Barnett, Y., Ly, L., Barnett, M., Chohan, G., Masters, L. (2019, September)

ECTRIMS 2019, Stockholm,11-13 September201

A deep learning approach for multiple sclerosis T-1 lesion-inpainting using non-local partial convolutions

Xiong,H., Wang,C., Tao, D., Barnett, M., Wang, C.

35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis ECTRIMS 2019, Stockholm,11-13 September 2019

Comparable Rates of Longitudinal Grey Matter Atrophy in Relapsing Multiple Sclerosis Patients Treated with Fingolimod and Healthy Controls Using Magnetic Resonance Imaging Analysis Techniques

Beadnall, H. N., Ly, L., Wang, C., Barton, J., Hardy, T. A., Zivadinov, R., & Barnett, M. H. (2019, March)

PACTRIMS 2018, Paris,1-3 November 2018

The Contribution of Subcortical Structures to Memory Impairment in Multiple Sclerosis

Devenney, E., Wang, T., Beadnall, H., Ly, L., Dawes, C., & Barnett, M. (2019, March)

PACTRIMS 2018, Paris,1-3 November 2018

Investigating the Mechanisms of Microstructural and Functional Changes in the Motor Pathway in Multiple Sclerosis

Garber, J. Y., Wang, C., Beadnall, H. N., Howells, J., Matamala, J. M., Kiernan, M. C., ... & Barnett, M. H. (2019, March)

PACTRIMS 2018, Paris,1-3 November 2018

Filling in the Gaps: Precision Magnetic Resonance Imaging Reporting in Multiple Sclerosis Clinical Practice

Beadnall, H. N., Barnett, Y., Ly, L., Wang, C., Billiet, T., Ribbens, A., ... & Barnett, M. H. (2019, March)

PACTRIMS 2018, Paris,1-3 November 2018

MS-GAN: GAN-Based Semantic Segmentation of Multiple Sclerosis Lesions in Brain Magnetic Resonance Imaging

Zhang, C., Song, Y., Liu, S., Lill, S., Wang, C., Tang, Z., You, Y., Gao, Y., Klistorner, A., Barnett, M., Cai, W. (2018)

2018 International Conference on Digital Image Computing: Techniques and Applications (DICTA 2018), Piscataway: Institute of Electrical and Electronics Engineers (IEEE)

Understanding Memory Impairment in Multiple Sclerosis – contributions of macro and micro-structural alterations in the thalamus and hippocampus

E. Devenney, T. Wang, H. Beadnall, L. Ly, C. Dawes, S. Liu, M. Barnett

ECTRIMS 2018, Berlin, 10-12 October 2018

Alteration of visual cortical microstructure is associated with pathology along the optic radiation in patient with MS: An asymmetry analysis of posterior visual pathway

C. Wang, A. Klistorner, J. Barton, H. Beadnall, L. Ly, S. Liu, J. Garber, S. Reddel, M. Barnett

ECTRIMS 2018, Berlin, 10-12 October 2018

Diffusivity data suggests progressive lesion-independent demyelination in NAWM of MS patients: a 5 year study

A. Klistorner, C. Wang, S. Liu, L. Graham, M. Barnett

ECTRIMS 2018, Berlin, 10-12 October 2018

Personalized Lesion Profiling in Multiple Sclerosis

S. Liu, A. Klistorner, C. Wang, Y. Gao, B. Gilchrist, Y. You, Y. Song, J. Yao, W. Cai, M. Barnett

Joint Annual Meeting of ISMRM-ESMRMB, Paris, France (2018)

Free Water Elimination Improves Tractography through Multiple Sclerosis Lesions

B. Gilchrist, S. Liu, C. Wang, O. Pasternak, Y. You, A. Klistorner

Joint Annual Meeting of ISMRM- ESMRMB , Paris, France (2018)

Automatic Segmentation of Thigh Muscle in Longitudinal 3D T1-weighted Magnetic Resonance (MR) Images

Z. Tang, C. Wang, P. Hoang, S. Liu, W. Cai, D, D. Soligo, R. Oliver, M. Barnett, C. Formusek, 2018

In MICCAI Workshop on Data-driven Treatment Response Assessment (2018)

Centrifugal pattern of progressive water diffusion increase in chronic MS lesions

A. Klistorner, C. Wang, M. Barnett

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017.

Long­term Disease Outcomes in Multiple Sclerosis Patients Categorised by Baseline Brain Volume and with No Disease Activity over 2 Years

M.H. Barnett, D. Silva, C. Wang, N. De Stefano, M. Battaglini, M.P. Sormani, R. Meinert, D. Tomic, D. Arnold

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Structure and function of the corticospinal tract and motor cortex in multiple sclerosis

J Garber, C Wang, H Beadnall, T Hardy, J M Capponi, J Howells, M Kiernan, MH Barnett

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Improving the accuracy of brain tissue loss assessment in patients with multiple sclerosis: a role for diffusion imaging?

C. Wang, J. Barton, A. Klistorner, L. Ly, H.N. Beadnall, S. Reddel, M.C. Kiernan, M.H. Barnett

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Multiple sclerosis: structure-function correlations in the cerebral cortex

H.N. Beadnall, C. Wang, J.M. Matamala, T.A. Hardy, J. Howells, C. Dawel, J. Garber, J. Barton, S. Reddel, M.C. Kiernan, M.H. Barnett

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

The effect of quantitative magnetic resonance imaging (QMRI) on no evidence of disease activity (NEDA) status in multiple sclerosis clinical practice: A multicentre retrospective longitudinal study

H. Beadnall, T. Billiet, D. Horakova, D.P. Ramasamy, L. Ly, A. Ribbens, M.G. Dwyer, T. Uher, C. Wang, N. Bergsland, E. Havrdova, E. Carl, W. Van Hecke, M. Vaneckova, R. Zivadinov, M.H. Barnett

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Conduction velocity in demyelinated cerebral white matter: a structure-function correlation study in optic radiation

C. Wang, J. Barton, A. Klistorner, L. Ly, H.N. Beadnall, S. Reddel, M.C. Kiernan, M.H. Barnett

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Accelerated loss of chronically demyelinated axons in relapsing-remitting multiple sclerosis

A. Klistorner, C. Wang, C. Yiannikas, J. Parratt, M. Barnett

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Lateral ventricular atrophy measurements agree better than whole brain measures across centers and measurement techniques

M. Dwyer, N. Bergsland1, D. Horakova, M. Vaneckova, T. Uher, E. Havrdova1, M. Barnett, H. Beadnall, C. Wang, T. Billiet, W.V. Hecke, A. Ribbens, R. Zivadinov

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Comparing magnetic resonance imaging brain atrophy measurement techniques in multiple sclerosis clinical practice: Longitudinal assessment

Beadnall HN, Wang C, Van Hecke W, Ribbens A, Barnett MH

Australian and New Zealand Association of Neurologists (ANZAN) Annual Scientific Meeting 2017 (Platform presentation). Gold Coast, Australia. 11 May 2017

The prognostic utility of No Evidence of Disease Activity (NEDA) Australian and New Zealand Association of Neurologists (ANZAN) Annual Scientific Meeting 2017 (Platform presentation)

Grace Lu, Heidi Beadnall, Chenyu Wang, Todd Hardy, Joshua Barton, Michael Barnett

Gold Coast, Australia. 11 May 2017

Durable Reduction in MRI Disease Activity With Alemtuzumab in the Absence of Continuous Treatment in Patients With Active Relapsing-Remitting Multiple Sclerosis Who Were Treatment-Naive: 6-Year Follow-up of the CARE-MS I Study

D. Arnold , M. Barnett, et. al

69th American Academy of Neurology (AAN) Annual Meeting (P4.374). Boston, United States of America. 26 April 2017

Alemtuzumab Durably Slows Brain Volume Loss Over 6 Years in the Absence of Continuous Treatment in Patients With Active RRMS Who Were Treatment-Naive (CARE-MS I) or Had an Inadequate Response to Prior Therapy (CARE-MS II)

A. Traboulsee, M. Barnett, G. Comi , C. LaGanke, D. Pelletier, A. Rovira , S. Schippling , D. Margolin , K. Thangavelu, K. Nakamura , D. Arnold , o. and CAMMS03409 Investigators

69th American Academy of Neurology (AAN) Annual Meeting (P4.374). Boston, United States of America. 26 April 2017

Decreased MRI Disease Activity Over 4 Years in Patients Who Switched From SC IFNB-1a: CARE-MS II Extension Study 4-Year Follow-up

D. Pelletier, M. Barnett, et. al Alemtuzumab

69th American Academy of Neurology (AAN) Annual Meeting (P4.374). Boston, United States of America. 26 April 2017

Improves Clinical Outcomes Over 4 Years in Patients With Relapsing-Remitting Multiple Sclerosis Who Discontinued SC IFNB-1a: CARE-MS II Extension Study 4-Year Follow-up

A. Boyko, M. Barnett, et. al Alemtuzumab

69th American Academy of Neurology (AAN) Annual Meeting (P4.374). Boston, United States of America. 26 April 2017

Alemtuzumab Suppresses MRI Disease Activity Over 6 Years in the Absence of Continuous Treatment in Patients With Active Relapsing-Remitting Multiple Sclerosis and an Inadequate Response to Prior Therapy: CARE-MS II

S. Schippling, A. Traboulsee, M. Barnett, et. al

69th American Academy of Neurology (AAN) Annual Meeting (P4.374). Boston, United States of America. 26 April 2017

Longitudinal brain atrophy measurement techniques in clinical multiple sclerosis practice using magnetic resonance imaging

Beadnall HN, Wang C, Van Hecke W, Ribbens A, Barnett MH

69th American Academy of Neurology (AAN) Annual Meeting (P4.374). Boston, United States of America. 26 April 2017

Assessment of Brain Atrophy in Multiple Sclerosis Patients in Clinical Routine: A Multi-Center Comparison Study of Radiological and Quantitative Reports

Ribbens A, Billiet T, Beadnall HN, Vaneckova M, Weinstock-Guttman B, Ly L, Wang C, Carl E, Claes L, Dwyer M, Krasensky J, Uher T, Horakova D, Van Hecke W, Barnett M, Zivadinov R

69th American Academy of Neurology (AAN) Annual Meeting (P4.373). Boston, United States of America. 26 April 2017

Association of Quantitative MRI to Radiological Reporting for the Evaluation of Lesion Burden Status in Multiple Sclerosis: A Multi-Center Study

Ribbens A, Billiet T, Beadnall HN, Vaneckova M, Weinstock-Guttman B, Ly L, Wang C, Ramasamy D, Houbrechts R, Bergsland N, Seidl Z, Uher T, Van Hecke W, Horakova D, Zivadinov R, Barnett M

69thAmerican Academy of Neurology (AAN) Annual Meeting (P4.358). Boston, United States of America. 26 April 2017

Alemtuzumab reduced MRI lesions and slowed brain volume loss in CARE-MS II patients switching from SC IFNB-1a: 5-year follow-up after alemtuzumab (TOPAZ study)

D. Pelletier, B, Barnett et. al

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Alemtuzumab decreased MRI disease activity and slowed brain volume loss over 5 years after switching from SC IFNB-1a: follow-up of CARE-MS I (TOPAZ study)

A. Rovira, B. Barnett et. al

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Patients with active RRMS experience durable reductions in MRI disease activity and slowing of brain volume loss with alemtuzumab: 7-year follow-up of CARE-MS II patients (TOPAZ study)

D. Pelletier

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Silent lesions on MRI

M.Min, M. Barnett et. al

shifting goal post for treatment decisions in MS,7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Durable reduction in MRI disease activity and slowing of brain volume loss with alemtuzumab in patients with active RRMS: 7-year follow-up of CARE-MS I patients (TOPAZ study)

D.L. Arnold, M. Barnett, et. al

7th Joint ECTRIMS-ACTRIMS meeting, Paris, 25 - 28 October 2017

Arterial spin labelling measurements of cortical perfusion in multiple sclerosis show widespread reduced cortical metabolism

Ruth Oliver, Heidi Beadnall, Chenyu Wang, Matthew Kiernan, Todd Hardy, Michael Barnett

ISMRM 25th Annual Meeting, electronic poster #1885, Honolulu, USA, 22-27 April 2017

Optic Radiation Reconstruction in Patients with Multiple Sclerosis: Template Based Approach vs. Individual Tractography Based Method

C. Wang, A. Klistorner, L. Ly, V. Fofanova, M.H. Barnett

ISMRM Workshop on Breaking the Barriers of Diffusion MRI, Lisbon, Portugal, 2016

Quantifying Lesion Progression in Multiple Sclerosis: a novel Magnetic Resonance Imaging pipeline

C. Wang, L. Ly, A. Klistorner, H. Beadnall, J. Barton, R. Oliver, M.H. Barnett

32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress, London, 14-17 September 2016

Automated segmentation of FLAIR lesion volume and number: Validation and comparison to manual inter-rater variability

C. Egger, R. Opfer, C. Wang, T. Kepp, L. Spies, M.P. Sormani, M. Barnett, S. Schippling

32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress, London, 14-17 September 2016

Diffusivity in multiple sclerosis lesions: at the cutting edge?

A. Klistorner, V. Fofanova, C. Wang, M. Barnett, J. Parratt, C. Yiannikas

32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress, London, 14-17 September 2016

Longitudinal assessment of brain lesion changes in follow-up MRI scans of patients with Multiple Sclerosis

Saurabh Jain, Annemie Ribbens, Diana M. Sima, Melissa Cambron, Jacques De Keyser, Chenyu Wang, Michael H Barnett, Sabine Van Huffel, Frederik Maes, Anke Maertens, Dirk Smeets

32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress, London, 14-17 September 2016

Comparison of cortical perfusion between relapse-remitting multiple sclerosis patients and healthy controls measured using Arterial Spin Labeling MRI

R.A. Oliver, L. Ly, H. Beadnall, C. Wang, T. Hardy, M.H. Barnett

32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress, London, 14-17 September 2016

A multicentre study of quantitative susceptibility mapping in sub-cortical deep gray matter structures in relapsing multiple sclerosis

R. Zivadinov, F. Schweser, C. Dawes, J. Hagemeier1, L. Ly, C. Wang, N. Bergsland, H. Beadnall, E. Carl, B. Weinstock-Guttman, R.R. Benedict, M. Barnett

32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress, London, 14-17 September 2016

The role of quantitative magnetic resonance imaging (QMRI) in clinical decision making in multiple sclerosis

H. N. Beadnall, L. Ly, C. Wang, R Oliver, G Lu, M. H. Barnett

Australian and New Zealand Association of Neurologists (ANZAN) Annual Scientific Meeting 2016 (Platform presentation – Young Investigator Session). Perth, Australia. 24-27 May 2016

Whole brain volume quantification in multiple sclerosis: ready for translation into clinical practice?

B. N. Heidi, C. Wang, T. Burke, R. Oliver, S.N. Hatton, J. Barton, L. Ly, S. Vucic, M.H.Barnett

American Academy of Neurology 68th Annual Meeting, Poster #209. Vancouver, Canada. 15-21 April 2016

Complete partial volume solution for ASL brain perfusion data applied to relapsing-remitting multiple sclerosis patients

R. Oliver, L. Ly, C. Wang, H. Beadnall, Il. B. Galazzo, M. Chappell, X. Golay, E. De Vita, D.Thomas, and M. H. Barnett

ISMRM 24th Annual Meeting, Poster #1976,Singapore, 10 May 2016

A novel MRI pipeline for assessing multiple sclerosis lesion evolution in the optic radiation

C. Wang, A. Klistorner, R.A. Oliver, L. Ly, M.H. Barnett

31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress. Barcelona, 7 - 10 October 2015

Tablet-based waiting room cognitive screening in a multiple sclerosis clinic

H.N. Beadnall, C. Wang, R.H. Benedict, C. Dawes, M.H. Barnett

31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress. Barcelona, 7 - 10 October 2015

Evidence of progressive demyelination and neurodegeneration in chronic MS lesions: DTI study

A. Klistorner, C. Yiannikas, J. Parratt, C. Wang, Y.T. Liu, S.L. Graham, M.H. Barnett

31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Congress. Barcelona, 7 - 10 October 2015

Degenerative changes in the optic radiation and the primary visual cortex in glaucoma patients: an MRI study

Y. You, M. Kaushik. C. Wang, S. Graham, A. Klistorner

The 6th World Glaucoma Congress, Poster #122, Hongkong 6-9 June, 2015

Quantifying brain atrophy: ready for translation to clinical practice?

C. Wang, H. N. Beadnall, T. Burke, R. Oliver, S.H. Hatton, J. Barton, L. Ly, S. Vucic M.B. Barnett

Australian & New Zealand Association of Neurologists (ANZAN) 2015 Conference (Platform Presentation #82). Auckland, New Zeatland. May 12-15, 2015

Whole Brain Volume Measurements in Multiple Sclerosis: Cross-Sectional Data Comparison Between Three Methods

C. Wang, H.N. Beadnall, S.N. Hatton, G. Bader, D. Tomic, D.G. Silva, M.H. Barnett

American Academy of Neurology 67th Annual Meeting Poster #P6.154. Washington, DC. 18-25 April 2015

(2014) Biomarkers of neurodegeneration in multiple sclerosis

Clarke AJ, Wang C, Beadnall H, Ghadiri M, Chohan G, Masters L, Barnett Y, Hatton SN, Lagopoulos J, Hagemeier J, Zivadinov R, Barnett MH (2014)

Clarke AJ, Wang C, Beadnall H, Ghadiri M, Chohan G, Masters L, Barnett Y, Hatton SN, Lagopoulos J, Hagemeier J, Zivadinov R, Barnett MH

Magnetic Resonance Spectroscopy Measurements In Normal-Appearing White Matter As A Biomarker Of Whole Brain White Matter Integrity In Relapsing Remitting Multiple Sclerosis

Hatton SN, Lagopoulos J, Wang C, Beadnall H, Ghadiri M, Chohan G, Masters L, Barnett Y, Barnett MH (2014)

7th Pan-Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS) Congress (Poster #P20). Taipei, Taiwan. 6-8 November 2014

Medial longitudinal fasciculus: a window on axonal function in multiple sclerosis& , Australian & New Zealand Association of Neurologists (ANZAN) 2014 Conference (Poster #62)

C. Wang, D. Paling, L. Chen, S. N. Hatton, J. Lagopoulos, S. T. Aw, M. C. Kiernan, M. H. Barnett

Sydney, Australia. May 18-22, 2014

Understanding mechanisms of axonal loss in non-optic neuritis eyes of multiple sclerosis patients& 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis & 18th Annual Conference of Rehabilitation in MS

A. Klistorner, P. Sriram, N. Vootakuru, C. Wang, M. Barnett, R. Garrick, J. Parratt, N. Levin, N. Raz, L. Masters, S. Graham, C. Yiannikas

Copenhagen, Denmark. 2~5 October 2013

Inner nuclear layer thinning is proportional to the loss of retinal ganglion cells in optic neuritis& 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis

M. Kaushik, A. Klistorner, C. Wang, M. Barnett, R. Garrick, J. Parratt, S. Graham, C. Yiannikas

18th Annual Conference of Rehabilitation in MS. Copenhagen, Denmark. 2~5 October 2013

Lesion Length Along the Medial Longitudinal Fasciculus Correlates with Neuroaxonal Conduction Delay in Multiple Sclerosis

C. Wang, D Paling, S Aw, MH Barnett, L Chen, S Hatton, J Lagopoulos

Multiple Sclerosis as a Whole-Brain Disease, ISMRM scientific workshop, London, England, UK, June 2013

Ganglion cells loss in non-optic neuritis eyes of MS patients

P. Sriram, N. Saakova, C.Wang, H. Arvind, S. Graham, C. Yianikus, R. Garrick, M. Barnett, J. Parrett, A, Klistorner

28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis, Lyon, France, October 2012

Retinal structure and function in eyes of Multiple Sclerosis patients with no optic neuritis

P. Sriram, N. Saakova, C. Wang, S. Graham, C. Yiannikus, R. Garrick, A. Klistorner

50th International Society for Clinical Electrophysiology of Vision Symposium, Valencia, Spain, June 2012